# IGF-1 LR3

Main Efficacy and Mechanism of Action of IGF-1 LR3

1. Significantly Enhanced Bioactivity

• Its growth-promoting activity and receptor binding capacity are significantly higher than those of ordinary natural IGF-1. In vitro bioactivity has even been described by some literature as far exceeding the levels of ordinary insulin or natural IGF-1.

2. Significantly Extended Half-Life

• Natural IGF-1 has a very short half-life in vivo (usually less than 10 minutes); while IGF-1 LR3, due to its difficulty in binding to IGF-binding protein (IGFBP) in vivo, has a half-life extended to approximately 24 hours (one day), thus allowing it to exert its effects more persistently in the circulatory system.

3. Promotes Protein Synthesis and Inhibits Protein Degradation

• It can enhance the efficiency of cellular utilization of amino acids and glucose, promote protein synthesis in muscle and other tissues, and reduce protein degradation.

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